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Sulfation and glucuronidation: Most of the acetaminophen will be metabolized through conjugation reactions using the SULT and UGT enzymes
This severe glutathione deficit was accompanied by elevated ventricular lactate, a clear biomarker indicating that the brains of these patients are relying on highly inefficient, oxygen-deprived anaerobic metabolism due to mitochondrial stress
However, following multiple overdoses which is the predominant mode of paediatric overdose has been reported [15, 51, 56,57,58]
Do not store reconstituted solutions of drugs for injection unless otherwise directed by the manufacturer of the solute
Glutathione S-transferases as emerging investigational targets [PMID: 12540261] Laboratory literature summary: Glutathione S-transferases as emerging investigational targets
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