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Mol Ther 11 : 745753
When to increase dose Consider increasing if: Minimal response after 4-6 weeks at current dose No side effects at current dose Current dose below the higher end of recommended range Goals not being met with conservative approach Increase gradually, typically by 25-50% at a time
Subcutaneous absorption of semaglutide is equivalent across sites (abdomen, thigh, upper arm)
Studies show that semaglutide helps people lose weight and keep it off for over a year with continued use
This combination is seen in tirzepatide (Mounjaro/Zepbound)
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