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Articles pertinent to the aim of the review were selected based on the relevance of the title and abstract in the topic by four authors (R.M.R., E.M., L.C., and C.V.) and then were critically evaluated by all authors
Helps lighten skin pigmentation such as acne scars, age spots, underarms, inner thighs & even private parts
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It has been suggested that keratinocytes, through the release of biological mediators, proopiomelanocortin (POMC)-derived peptides, basic fibroblast growth factor, and endothelins, regulate proliferation and differentiation of melanocytes and stimulate melanogenesis through receptor-mediated signalling pathways [20]
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