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In cultured human keratinocytes exposed to UVB radiation (a standard oxidative stress model), pre-treatment with 10 nM GHK-Cu resulted in: 2.8-fold increase in glutathione reductase mRNA (the enzyme regenerating reduced glutathione from its oxidized form) 2.3-fold increase in catalase expression (HO decomposition) 1.9-fold increase in ferritin heavy chain (sequestering iron, another Fenton-active metal) 62% reduction in 8-hydroxy-2-deoxyguanosine (8-OHdG) levels, a DNA oxidative damage marker The protective effect disappeared when using copper-free GHK or copper chloride alone, confirming the intact peptide-copper complex is required
It is, therefore, recommended that SAMe should be administered on an empty stomach
What's the difference vs KLOW Blend
Maintenance phase reduces to 2-3mg once weekly for 4-8 weeks to sustain healing progress
US$ 22.93
US$ 25.22
US$ 21.78
US$ 23.18
