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Diabetic neuropathy mainly comprises distal symmetric polyneuropathy, leading to sensory loss, pain, and motor dysfunction, and can result in diabetic foot ulcers requiring lower-limb amputations
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The selectivity is documented in the foundational paper: a peer-reviewed European Journal of Endocrinology study demonstrating that Ipamorelin stimulates growth hormone selectively without elevating ACTH, cortisol, or prolactin, which is exactly why it has become the default selective secretagogue in modern peptide medicine
Ipamorelin is generally well-tolerated, but its dose matters
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