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Important safety considerations include a boxed warning regarding thyroid C-cell tumors observed in rodents (though the relevance to humans is unknown) and contraindications for patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
We combine orthogonal analytical approaches to confirm composition, assess purity, and provide structure-relevant evidence that supports metabolite assignment, method development, or repeat synthesis decisions
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The intensely labeled structures in the ventral funiculus correspond to the location of the fiber bundles of CSF-contacting neurons 31,32,33