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Some specific ways to help manage lipedema include: Wearing compression garments to help lymph flow Gentle exercises, like walking or swimming, to support joints Eating a balanced diet with lots of fresh foods Managing weight in a healthy, steady way Getting manual lymphatic drainage or gentle massage Using supplements that support tissue and nerve health Tracking symptoms and changes with a healthcare team Reaching out for mental health support when needed Establishing a support system of family, friends, and fellow patients

Bayesian sensitivity analyses were conducted for validation

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Compounded semaglutide and tirzepatide are not approved by the FDA and have not been evaluated for safety, effectiveness, or quality by the FDA