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While dermatologists are seeing potential benefits of using GLP-1s as part of a comprehensive treatment approach, no therapy is right for everyone. Some of the limitations and risks associated with GLP-1 use include: Side effects many people experience side effects like nausea, vomiting, gallbladder disease, and GI discomfort
Retinal pigment epithelial cells express a functional receptor for glucagon-like peptide-1 (GLP-1)
In parallel, other researchers are exploring alternative models of use, such as starting with GLP-1 drugs for a short period to achieve initial weight loss, then switching to lifestyle programs, meal replacements or older medications for maintenance rather than keeping patients on GLP-1 drugs for the rest of their lives