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10.3322/caac.21660 241 SurhY.-J.ChunK.-S.ChaH.-H.HanS
Acyl coenzyme A synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) are intermediate factors essential for activating fatty acids to drive lipid peroxidation and execute ferroptosis
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Taken together, these findings suggest that carnitine pool homeostasis is closely related to inflammatory and immune homeostasis, tumor development, and immune escape, providing new perspectives and potential targets for the treatment of inflammatory diseases and cancer
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