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The drug has experienced rapid adoption, with prescription share increasing to 63% among GLP-1 users by 2023, reflecting strong physician preference for its efficacy
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Gastrointestinal reactions and digestive issues are linked to Ozempic use, including upset stomach (dyspepsia), burping (eructation), gas (flatulence) and gastroesophageal reflux disease
In a meta-analysis of 60 studies involving 60,077 T2D patients, GLP-1RAs marginally reduced the UACR in comparison to placebo and other antidiabetic agents, but resulted in no clinically relevant changes in eGFR ( Renoprotective Mechanisms of GLP-1RAs Experimental studies to elucidate the beneficial effects on DKD have been extensively reported
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