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For instance, in NSCLC, treatment with first- and second-generation EGFR tyrosine kinase inhibitors (TKIs) often leads to the development of the EGFR T790M mutation, while third-generation inhibitors subsequently select for the C797S mutation, both of which confer resistance
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Notably, both MASLD and ALD exhibit similar histology and share some pathological mechanisms, reinforcing the idea that altered metabolic homeostasis in the liver and adipose tissue is the final common pathway driving liver injury (Kalligeros et al
Protective effects of tartary buckwheat flavonoids on high TMAO diet-induced vascular dysfunction and liver injury in mice
Additionally, it remains active for prolonged periods, aiding in appetite regulation and blood sugar maintenance throughout the day
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