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A significant proportion of the published work comes from a single research group the Zagreb laboratory associated with Sikiric and colleagues
No hepatotoxicity has been documented in published human trials lasting up to 12 weeks or in 90-day rodent toxicology studies
Severe deficiencies, especially those with neurological symptoms (numbness, tingling, memory issues), often require a more intensive initial treatment plan to rapidly restore healthy B12 levels and prevent lasting nerve damage
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