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51 One significant challenge is the high rate of gastrointestinal adverse events associated with these compounds, which may be related to their pharmacokinetic properties and direct gastrointestinal irritation
Conversely, when the body is too cold, it reduces blood flow to the skin and initiates shivering to generate heat
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Effects of DSIP on narcolepsy
The GIPR missense variant, rs1800437, has been associated with a large number of traits in the public domain, including BMI and body mass phenotypes, T2D, blood glucose and a number of metabolic or haematologic traits including blood pressure, reticulocyte and/or erythrocyte volume and urinary calculus (Supplementary Table 18)
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