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Native GLP-1 is rapidly cleaved (half-life of 1 to 2 min) by the ubiquitously expressed serine protease dipeptidyl peptidase-4 (DPP-4) and undergoes quick renal elimination [34, 4042]
It delivers the look of firmer, smoother skin, minimizes the appearance of dark under-eye circles, and enhances skin vitality for eyes that look brighter, fresher and younger
A completely different molecule
Appetite and weight changes require consideration from both directions
Future studies incorporating individual-level data and additional clinical endpoints are warranted to further refine these estimates
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