Longterm use of GLP1 receptor agonists is generally welltolerated, but clinicians should monitor for gastrointestinal side effects, rare risks like pancreatitis, and individual response
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Eating smaller and more frequent meals is another strategy that can help ease stomach discomfort
However, decongestant medications are not a long-term solution
Recent FDA approvals have expanded the indication for semaglutide to include the reduction of major adverse cardiovascular events (MACE), such as heart attack, stroke, and cardiovascular death, in adults with established cardiovascular disease and obesity