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The hydroxyl group in the chromanol head of -tocopherol donates a hydrogen atom to neutralize lipid peroxyl radicals, halting their propagation in membranes and circulating lipoproteins
Studies have found that the longer cellular damage is allowed to occur, the more cellular function is impaired, giving way to the accumulation of even more damaged cells and accelerated aging
It detoxifies the liver, preventing conditions like fatty liver disease
Optineurin inhibits NLRP3 inflammasome activation by enhancing mitophagy of renal tubular cells in diabetic nephropathy
doi: 10.1007/s00394-020-02225-0 20
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