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All treatments were administered at study centers by trained investigators
Driving to a weight management clinic isnt realistic
Dopamine is known to play a role in reward and pleasure pathways in the brain
doi: 10.1016/j.molmet.2021.101240 88 LudwigMQChengWGordianDLeeJPaulsenSJHansenSNet al
PDE1B is enriched in the medium spiny neurons (MSNs) of the direct pathway, while PDE10A is highly expressed in the MSNs of both the direct and indirect pathways (Lakics et al., 2010)
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