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CAP acts on the large ribosomal subunit (LSU) by inhibition of peptide bond formation, thereby stalling mitoribosomes resulting in loss of mitochondrial translation with subsequent loss of mitochondrial-encoded respiratory chain complexes (Figs
GPX3, similar to GPX1, is located at a low level of the selenoprotein level and is sensitive to selenium content in the body, so it is often used as a biological marker to measure selenium content in the body
Feb 2010;8(2):159-65
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