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GLP-1 RAs showed a trend toward favorable neurological outcomes, including improved cognitive function in individuals with AD/MCI, reduced dementia risk in individuals with T2DM, and improvements in Parkinsons disease scores

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Lower levels of IGF-1 and growth hormone in older adults have been linked with (5, 14): increased fat mass increased cardiovascular risk decreased muscle mass and strength lower cognitive function lower bone density limited joint mobility Several of these traits are seen in frail older adults

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