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Here, in this randomized, double-blind, placebo-controlled trial, participants ( n = 98) were randomly assigned to 48 weeks of once-weekly subcutaneous retatrutide (1, 4, 8 or 12 mg dose) or placebo
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At the 12 mg dose, systolic blood pressure dropped by 14.0 mmHg, with reductions in non-HDL cholesterol, triglycerides, and high-sensitivity CRP (a marker of inflammation)
During T cell activation, theres a conspicuous surge in amino acids linked to this metabolism
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