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31, 32 When a conclusive mtDNA abnormality could not be identified, nuclear mitochondrial gene testing and/or a muscle and/or skin biopsy was recommended

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In order to protect the body from UV damages, melanocytes (~510% of epidermis cells), also located in the basal layer of the epidermis, strongly bind to several keratinocytes (~35 10 ) delivering them melanin, an UV absorbing molecule