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In mice plasma TMAO has been shown to be higher in female and TMA lower compared to males as Flavin-Containing Monooxygenase 3 (the main TMAO producing enzyme) expression is drastically downregulated by testosterone (and mildly upregulated by estrogen
Meister, A
Deuterated phospholipids (Avanti Polar Lipids) were used as internal standards
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References NHS: British Skin Foundation: PubMed (UK access): NICE (National Institute for Health and Care Excellence):
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