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The end result is improved blood sugar control and often significant weight loss clinical trials have shown patients losing in the order of 1520% of body weight on some of these drugs (3)
clinical efficacy and parameters affecting the response in real-world practice
The honest answer: if the research question is weight-loss ceiling or hepatic fat, retatrutide justifies the switch
If your baseline exam reveals moderate or worse diabetic retinopathy, your prescribing doctor may choose to start semaglutide at a lower dose and increase it more gradually
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