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And this axis plays a key role in reproductive function
Tryptophan is also a precursor to serotonin, and elevated serotonin levels can get in the way of effective conversion of the thyroid hormone T4 into T3, the active thyroid hormone and suppress thyroid hormone production
Approximately 50% of patients treated with oral therapies progress to insulin replacement, which then exacerbates weight gain and further complicates the disease
PMID 16307945
Epub 2009 Mar 16
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