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This is important because rapid IV administration can lead to sudden shifts in electrolytes particularly potassium which may result in hypokalemia and, in severe cases, cardiac complications

This is the standard choice for most in vivo preclinical protocols

Your injection dose depends entirely on getting the right concentration, so every step below deserves your full attention

Aseptic Access: Every time you withdraw a sample for measurement, use a new sterile syringe and a fresh alcohol swab on the stopper

Acta Orthop Scand 71:316321 Ethics declarations Conflict of interest The authors declare that they have no conflict of interest