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Semaglutide's most common adverse effects are gastrointestinal
The glucagon receptor arm the feature that distinguishes retatrutide from earlier-generation incretin compounds drives hepatic glucose metabolism, lipid oxidation, and energy expenditure effects, all absent from GLP-1 mono-agonists and dual GLP-1/GIP agonists
DPP-4 inhibitors have broad therapeutic applicability
Most GLP-1 medications, whether branded or compounded, have specific temperature requirements
The company also markets two other brands of semaglutide: Wegovy, used for weight management in obese adults, and Rybelsus, used to improve blood glucose control in adults with type 2 diabetes
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