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The Saxagliptin Assessment of Vascular Outcomes (SAVOR-TIMI 53) study is a similar study in 12,000 patients comparing saxagliptin with placebo in diabetic patients with high cardiovascular risk

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Plan reorder timing to account for: Supplier lead time (typically 3-7 business days for domestic orders, 2-4 weeks for international) Testing time if you verify each new batch (add 1-2 weeks for third-party testing) Buffer stock (maintain enough supply to cover 4-6 weeks of protocol even if a reorder is delayed) A practical reorder trigger for most researchers is when remaining stock drops below 8 weeks of protocol supply