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In addition to biological activity as an essential intracellular antioxidant, GSH facilitates the clearance of metabolic waste via GSH- S -transferases and may function as a neuropeptide

BPC-157 is a laboratory-synthesized peptide modeled from a protective compound originally identified in gastric secretions

For example, lung cancer cell-lines show different sensitivities to doxorubicin in the form of GSH depletion, with A549 and GLC 4 210(S) cells experiencing approximately 50% and 64% GSH depletion after a 12 hour exposure to 70 nM and 5 nM (per million cells) respectively 37