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These typically occur when starting treatment or increasing the dose and improve as the body adjusts
Furthermore, CPN-9, a novel NRF2 activator, is neuroprotective against mutant SOD1 H46R motor deficits and disease progression in mice (Kanno et al., 2012)
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Our calculated R-factor was 2.7, indicating a mixed hepatocellular and cholestatic pattern of injury
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