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GLP1 secretagogue cinnamaldehyde upregulates GLP1/PI3K/AKT and Nrf2 pathways to exert neuroprotection in a rotenone induced mouse model of Parkinsons disease

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1001-A G-CSF-MOBILIZED AUTOLOGOUS PERIPHERAL BLOOD CD34-POSITIVE CELL INFUSION THERAPY FOR HCV-RELATED DECOMPENSATED CIRRHOSIS Toru Nakamura 1,2 , Atsutaka Masuda 1,2 , Makoto Kako 3 , Hirayuiki Enomoto 4 , Masaki Kaibori 5 , Yasuyuki Fujita 6 , Kyoko Tanizawa 6 , Tetsuya Ioji 6 , Hideki Iwamoto 1,2 , Hironori Koga 1,2 , Hiroyuki Suzuki 1,2 , Tomoyuki Takashima 4 , Haruki Uojima 3,7 , Hidekazu Yamamoto 5 , Kazunori Yoh 4,8 , Atsuhiko Kawamoto 6 , Shuhei Nishiguchi 4,9 , Takuji Torimura 1,10 and Takumi Kawaguchi 1 , (1)Kurume University School of Medicine, (2)Research Center for Innovative Cancer Therapy, Kurume University, (3)Shonan Kamakura General Hospital, (4)Hyogo Medical University, (5)Kansai Medical University, (6)Foundation for Biomedical Research and Innovation at Kobe, (7)Research Institute, National Center for Global Health and Medicine, (8)Yoh Digestive Clinic, (9)Kano General Hospital, (10)Omuta City Hospital Background: Preclinical studies have shown that peripheral blood (PB)-CD34 + cell transplantation reduced established liver fibrosis and promote hepatic regeneration