A phase II trial focusing on individuals with overweight or obesity, coupled with hypertension or dyslipidemia but without T2D, found that cagrilintide (2.4 mg) alongside diet and exercise, led to a 10% body weight reduction compared to 3% with placebo over 26 weeks [99]
[20] Pekala J, Patkowska-Sokoa B, Bodkowski R, Jamroz D, Nowakowski P, Lochyski S, Librowski T.Curr Drug Metab
Timeline: When You'll Notice Weight Loss Changes Most patients begin noticing appetite suppression within the first 12 weeks of starting GLP-1 therapy, though visible weight loss typically appears around weeks 36
Randomized controlled trials will be necessary to determine if the observed reductions in cancer risk are real and meaningful from a clinical perspective
However, are these injections effective