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[1] These outcomes substantially exceeded placebo and represent some of the largest weight reductions reported in a controlled obesity trial

Magliano DJ, Boyko EJ

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Notably, many participants in these trials saw their OSA severity downgraded from moderate-to-severe to mild, and some experienced remission of OSA entirely

When to consider GLP-1 microdosing Based on current clinical practice patterns, practitioners are most commonly recommending GLP-1 microdosing in these scenarios: Partial responders: Patients on standard therapy who have improved but still experience breakthrough flares, residual inflammation, or persistent symptoms