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The generation of an effective immune response to vaccines, or to various infections, involves the usage of large amounts of active vitamin B2, as it is used in the activation of over 100 B2 dependent enzymes, 130 B6 dependent enzymes, and the cycling of methyl B12 which is used in over 200 B12-dependent methylation enzymes, the activation and processing of iron and also activation and processing of vitamin D
Some people may also suffer from pernicious anemia, which inhibits the body from being able to absorb enough vitamin B12, causing a deficiency
Display technologies enable high-throughput screening of diverse randomized peptide libraries 41 and human-proteome-derived libraries 42,43 but typically require purified protease, which can pose challenges for unstable or difficult-to-express protease variants
Some individuals may experience mild digestive upset if they have a very sensitive stomach, which can usually be managed by taking the supplement with food
