Reynolds JC, Lai RW, Woodhead JST, Joly JH, Mitchell CJ, Cameron-Smith D, Lu R, Cohen P, Graham NA, Benayoun BA, Merry TL, Lee C
Interestingly, lipidation can shield potential interaction sites on the molecule, reducing the impact of NSA
However, the long-term effects of semaglutide on this condition havent been thoroughly studied, so we dont know if sustained glucose control will improve the situation over time
However, it is essential to maintain a balanced perspective, recognising both the potential benefits and the need for continued research and careful medical supervision
Other evidence also suggests that GLP-1R in the cerebral cortex affects hedonic feeding by targeting areas involved in reward and addiction (110)