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Clinical studies, including SURMOUNT-4, have shown that patients who discontinue GLP-1 receptor agonists typically regain a significant portion of lost weight within the first year
The prognostic impact of the reactive hyperemia index (RHI) in HFpEF patients suggests that endothelial dysfunction may not be merely a passive finding, but rather that endothelial function plays an active and crucial pathophysiological role in HFpEF [23]
Patients often report significant weight reduction, which is maintained with continued treatment and lifestyle changes
Most people lose 5-10% of their initial weight on these medications
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