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NPI-001 depleted cystine from human cystinosis fibroblast cells in culture statistically significantly greater than cysteamine

The study took place over 4 days - incorporating 3 days of dietary adaptation followed by a day dedicated to quantifying GSH synthesis in red blood cells

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Biomarkers depend on the compound used and the target mechanism: Le NAD + and the glutathione These are endogenous molecules naturally present in the human body

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