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In addition, NRF2 is regulated by the cytoplasmic inhibitor Kelch-like ECH-associating protein 1 (KEAP1)
Thus, at each of these three stages of heme transfer, namely cell uptake, release from mitochondria and macrophage breakdown there is no necessity for heme to enter the cytosol
By understanding the vital role of glutathione in our health, we can take proactive steps to enhance our well-being and ensure our bodies are equipped to handle the challenges of daily life
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