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Trials use eligibility criteria, informed consent, scheduled monitoring, and study-site oversight

Several technologies have been explored to discover and develop a GLP-1RA applicable for once-weekly (OW) dosing

Ongoing research is focused on understanding the pathways through which GLP-1 impacts mental health and evaluating the clinical benefits of these medications in patients with mood disorders

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Wootten D, Reynolds CA, Smith KJ et al (2016) The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism