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Chronic METH abuse causes severe and persistent damage to the central nervous system (CNS), leading to cognitive deficits, psychiatric symptoms, and motor dysfunction
Nor are they a cure
"Your firms corrective actions only included scrapping devices in inventory and increasing the cleaning frequency of the [redacted] machine to prevent excess silicone from migrating to the luer connector, despite receiving 221 complaints and filing 177 [medical device reports (MDR)] for the disconnection of the NAMIC Angiographic Control Syringes from manifolds which impact patients and clinicians, including one (1) MDR # 3015910259-2025-00109 involving the injection of air into a patient (Complaint # [redacted] dated [redacted]) and one (1) MDR # 3015910259-2024-00045 involving biohazard exposure of a clinician (Complaint # [redacted] dated [redacted])." Furthermore, Medline Industries was cited for other violations, including failing to maintain schedules for adjusting, cleaning, and performing other equipment maintenance to ensure compliance with manufacturing specifications
Interestingly, reproductive responses were partially different in the PCOS model of preserved ovulation, since treatment of PNA mice with a low dose of GLP1/E was capable to elevate LH levels and reversed, to a large extent, the ovarian cycle irregularities observed in PNA mice treated with vehicle
Standard injectable dosing ranges from 2-5mg administered 2-3 times weekly
