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4,12 Four agentsalendronate, risedronate, zoledronic acid, and denosumabhave evidence for broad spectrum anti-fracture efficacy and are considered initial options in most cases
The first 3 months are the critical window Shedding that goes unaddressed early leads to avoidable density loss
Apr 2011;24(2):237-242
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However, most trials recruited relatively healthy, non-drinking or light-drinking populations, so data specifically examining heavy drinkers on GLP-1 therapy is limited
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