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Mechanistic information has been published on how glutathione deactivates mutagens through the activity of various glutathione dependent enzymes such as glutathione S-transferase [2] and glutathione peroxidase [3]

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The NEP study probably indicates the trend while not being the actual enzyme that determines the in vivo half-life of our analogues

doi: 10.3389/fnmol.2019.00109 69 NardiLChhabraSLeukelPKrueger-BurgDSommerCJSchmeisserMJ