Tirzepatide alone achieves 20-22% weight loss in SURMOUNT trials, while orlistat alone achieves 3-5%
Mechanistically, testosterone still has a clear role in improving insulin sensitivity indirectly by promoting fat loss and muscle growth, both of which enhance the bodys ability to regulate blood sugar, says Lee
While, previously, patients with severe OSA would likely require CPAP therapy for the remainder of their lives, especially as OSA tends to worsen with age and weight increase, these obesity-targeting medications offer the potential for some patients to become less dependent on CPAP or be managed using lower, more tolerable pressures. Indeed, patients on tirzepatide had about a 50% reduction in the apnea-hypopnea index and significant improvements in hypoxemia
But when you're on Ozempic, protecting your muscles becomes just as important as losing fat
The bigger risk is contamination if the needle has touched anything other than the inside of the vial