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Based on these results, the 1-year extension period in Evoke and Evoke+ will be discontinued

The triple therapy of metformin, a DPP-4 inhibitor and a SGLT-2 inhibitor has a very low treatment related hypoglycaemia risk, leads to a further, almost additive reduction of glycaemic parameters, a body weight loss in the same range as with a mono- or dual therapy with a SGLT-2 inhibitor and also to the expected SGLT-2 inhibitor induced reduction of blood pressure

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Alternatively, oral capsules are available but have significantly lower bioavailability

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