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FDA raised concerns about impurities, aggregates, endotoxins and immunogenicity
Results take six to eight weeks to show after treatment
HLA class I molecules (e.g., HLA-A, -B) also contribute to increased risk, particularly in certain populations (e.g., HLA-A24:02 in Asia)
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doi: 10.1186/s13568-025-01824-6 113 FanX.ChenL.ChenM.ZhangN.ChangH.HeM.et al
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