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In the 1960s, neutrophils were shown to undergo granule fusion with phagocytic vesicles following the engulfment of bacteria, later known as degranulation, following which the contents of the granules were decreased, indicating that neutrophils have a pathogen-fighting function

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)

doi:10.1016/j.phrs.2018.02.015

doi: 10.3390/ijms26125823 370 LiaoJ-FChengY-FYouS-TKuoW-CHuangC-WChiouJ-Jet al

The compound remains in a regulatory gray area: recognized as safe, but without the efficacy data needed for pharmaceutical approval