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James KellerShabrokh, D.O., at CPM
The interaction very rarely results in a pernicious anemia that appears reversible with discontinuation of metformin or with Methylcobalamin, vitamin B12 supplementation
Whilst B12 injections (hydroxocobalamin) are licensed NHS medicines for treating confirmed deficiency states such as pernicious anaemia, lipotropic injections lack MHRA marketing authorisation and robust clinical evidence
additionally, a domain-specific assessment using the Cochrane Risk of Bias Tool (RoB 2) was also conducted and reported in Table 3 to provide a comprehensive appraisal
[16] [17] The term "pernicious" means "deadly", and this term came into use because, before the availability of treatment, the disease was often fatal
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