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Combined outcome (Figure 2): 32.7% vs 16.1% showing semaglutide doubled the likelihood of simultaneous resolution + fibrosis improvement

For people with osteoarthritis, preserving both is important for joint stability and long-term mobility

These combined actions make semaglutide highly effective for both weight loss and blood sugar management

Delays can arise from clinical trial results, regulatory review, or production issues

Although homocysteine levels increase with age, a reduction in the cardiovascular risk associated with hyperhomocysteinemia also has been reported in subjects older than 45 years (Reis et al, 1995)