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490 In recent years, an increasing number of studies have explored the complex mechanisms of p53 under different physiological conditions and the influences and mechanisms of p53 mutations

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Human relevance of thyroid C-cell tumors in rats is unknown and could not be determined by clinical studies or nonclinical studies [see Boxed Warning, Warnings and Precautions (5.1)]

The most significant risk is hypoglycemia, where blood sugar drops too low