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The outer thigh has fewer nerves and blood vessels, which helps reduce the discomfort associated with the injection
This usually occurs in individuals with underlying digestive conditions, those who have trouble absorbing all nutrients through digestion, or those with pernicious anemia, which specifically prevents B12 absorption
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Moreover, use of sterile water may only dilute the safety as well as stability level of this antidiabetic medication
Special population studies, including evaluation in elderly patients, patients with significant comorbidities, and patients with organ dysfunction, would help establish safety profiles for diverse clinical populations
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