Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH et al
This delicate balance is an interplay between ROS production and the up-regulation of the AOX pathways CAT and GSH which opposes the apoptotic process (124)
As a result, you may experience the following symptoms ( tiredness a lack of energy shortness of breath difficulty concentrating more frequent bouts of illness difficulty regulating your body temperature or often feeling cold pale skin heart palpitations headaches hearing ringing, hissing, or buzzing noises inside your head itchiness a sore tongue or difficulty swallowing changes in the way food tastes hair loss cravings for non-food items, such as ice or dirt also known as pica painful open sores in the corners of the mouth spoon-shaped nails an uncontrollable urge to move your legs also known as restless leg syndrome If youre experiencing any of these symptoms, consider discussing diagnostic testing options with your healthcare provider to identify or rule out low iron levels or IDA
doi: 10.1016/j.jhep.2021.03.014 59
Factors such as dietary B12 intake, baseline B12 stores, concurrent medications, and individual absorption capacity all influence whether deficiency develops